Assistant Professor (f/m/x) in Warsaw

Mossakowski Medical Research Institute, Polish Academy of Sciences

Organisation/Company Mossakowski Medical Research Institute, Polish Academy of Sciences Department Department of Immunology Research Field Medical sciences » Cancer research Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions Other Positions Application Deadline 23 Nov 2026 - 23:59 (Europe/Warsaw) Country Poland Type of Contract To be defined Job Status Full-time Hours Per Week 40 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number SDI.111.14.2026 Is the Job related to staff position within a Research Infrastructure? No

Offer Description The current research program of the Department of Immunology:

Research conducted at the Department of Immunology of the Mossakowski Medical Research Institute, Polish Academy of Sciences (MMRI PAS), focuses on mechanisms regulating immune cell activation and cancer immunotherapy using monoclonal antibodies, effector cells, and cells engineered to express chimeric antigen receptors (CARs). Particular attention is paid to mechanisms of immunosuppression within the tumor microenvironment and factors limiting the efficacy of immunotherapy. We conduct both basic research in cancer immunology and translational research aimed at improving the effectiveness of cancer treatment.

The area of the research in which the candidate would participate:

investigating the impact of immunosuppressive mechanisms within the tumor microenvironment on the efficacy of CAR-T-cell therapy;

developing novel CAR-T-cell therapeutic strategies targeting the elimination of immunosuppressive tumor-associated macrophages (TAMs);

optimizing and functionally evaluating CAR constructs in in vitro models.

Description of job position activities:

designing, organizing, and conducting experiments investigating the effects of immunosuppressive factors within the tumor microenvironment on the survival, effector functions, and antitumor activity of immune cells in in vitro models;

generating and culturing T cells genetically modified to express chimeric antigen receptors (CAR-T cells);

testing and optimizing CAR constructs designed to eliminate tumor-promoting macrophages;

isolating human monocytes from blood;

differentiating and polarizing human macrophages;

performing functional assays to evaluate the cytotoxic activity of CAR-T cells in in vitro models;

actively participating in national and international scientific conferences;

analyzing, processing and presenting of research data;

preparing manuscripts for international scientific journals;

applying for external research funding, including preparing individual and consortium-based grant proposals;

actively participating in the implementation of research projects, in accordance with the requirements of the financing institution;

actively participating in the scientific and educational activities of the Department and Institute, including supervising students involved in the Student Scientific Society;

engaging in science communication and outreach activities;

implementing new technologies and research methodologies to improve the quality of scientific research;

actively participating in seminars, courses, and trainings.

Requirements Research Field Medical sciences » Cancer research Education Level PhD or equivalent

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

Requirements:

at least a Ph.D. degree in medical, biological or related sciences;

at least two original research articles published in journals listed in the Journal Citation Reports (JCR), including at least one publication as first author, co-first author, or corresponding author, published after obtaining the doctoral degree and not containing results from the doctoral dissertation;

experience in culturing cancer cell lines;

experience in isolating and culturing immune cells from blood;

very good knowledge of flow cytometry;

ability to analyze and present research findings;

active participation in international scientific conferences;

ability to work independently, excellent organizational and teamwork skills, creativity, and openness to new challenges;

documented experience in preparing research funding applications;

designation of MMRI PAS as the primary place of employment;

very good command of written and spoken English and Polish.

Specific Requirements

Additional requirements (desirable):

experience in supervising students or junior members of a research team;

experience working with lenti- and retroviruses under BSL-2 conditions;

experience in genetically modifying primary T cells using CAR vectors;

experience in performing functional assays using CAR-T cells;

experience working with human macrophages;

knowledge of immunosuppressive mechanisms associated with the tumor microenvironment and their impact on the efficacy of cellular immunotherapy;

documented experience in successfully securing research funding.

Languages ENGLISH Level Excellent

Languages POLISH Level Excellent

Research Field Medical sciences » Cancer researchBiological sciences » Biology

employment at one of the leading scientific institutions in Poland;

employment contract (full-time position);

opportunity for scientific development and independence in project management for which funding was obtained independently by the candidate;

participation in the implementation of other projects;

opportunity to attend conferences and to participate in internships abroad;

additional support from the social fund (i.e. support in difficult life situations, childcare subsidies and low interest loans);

possibility to join Employee Capital Plans (PPK);

additional benefits such as opportunity to join a group life insurance program, medical service package, and a Multisport card on preferential terms;

work in a good team, in a nice atmosphere;

friendly work environment.

Work Location(s) Number of offers available 1 Company/Institute Mossakowski Medical Research Institute, Polish Academy of Sciences Country Poland City Warsaw Postal Code 02-106 Street 5 Pawinskiego Street Geofield